- "...which is what happens when you call the feds..."
- ―Malcolm Reynolds
Also known as "the feds", federal agents were a law enforcement arm of the Union of Allied Planets. Agent McGinnis, was the leader of a "small battery" of Feds at Saint Lucy's hospital who managed to briefly apprehend River and Simon Tam and Jayne, but lost them again.
They were similar to the Federal marshals.