Serenity can refer to:
- Serenity - The Firefly-class transport captained by Malcolm Reynolds.
- Serenity (episode) - The pilot episode of the television series Firefly.
- Serenity (film) - The motion picture based on the television series Firefly.
- Serenity (novelization) - The novelization of the motion picture written by Keith R.A. DeCandido.
- Serenity (soundtrack)
- Serenity: Those Left Behind, also known as Serenity - The Dark Horse Comics miniseries that bridges the events of "Objects in Space" with the events of the motion picture.
- Serenity: Better Days - The comic book series, which explores some plot lines that the Firefly TV series was originally to explore.
- Serenity (Comic) - a short comic story set after the events of the film Serenity and given out for free on Free Comic Book Day by Dark Horse
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